Male Specific Issues
Loss of testosterone; the male sex and growth hormone
Narrowing of the chest resulting in respiratory disorders
Failure to extrude the penis
Loss of testosterone is directly correlated to: heart disease and myocardial infarction, strokes and cardiovascular disease, senile dementia, osteoporosis and hip fracture
Increases risk of cardiac hemangiosarcoma (by a factor of 1.6)
Increased risk of progressive geriatric cognitive impairment
Quadruples risk of prostate cancer(prostatic adenocarcinoma)
Female Specific Issues
Loss of estrogen; the female sex and growth hormone
Intervertebral disk disease
Myasthenia Gravis; muscle weakness
Altered moods leading to nervousness, separation anxiety, and digestive disorders
Doubled risk of splenic hemangiosarcoma
Five times the risk of cardiac hemangiosarcoma
Causes urinary spay incontinence
Three to four times the risk of urinary tract infections
Increased risk of recessed vulva, vaginal dermatitis, and vaginitis
Common Issues
Anesthesia shock and surgical complications
Post operative pain and infection
Personality changes
Increased risk of obesity (triple risk in males, double in females)
Tripled risk of hypothyroidism
Increased risk of osteosarcoma (bone cancer) in medium/large breeds when neutered before 1 year of age.
Cerebellar cortical abiotrophy (a neurological problem)
Doubled risk of urinary tract cancer
Increased risk of orthopedic disorders and hip dypslasia
Increased risk of adverse reactions to vaccinations